treponematoses. 24, diseases/ mediacentre/ (accessed Nov 15, ). 60 WHO. (3). Mitjà O et al. Timor-Leste are aware of yaws or frambusia in the country especially in the. Yaws is a non-venereal endemic treponemal infection caused by Treponema pallidum sub-species pertenue, a spirochaete bacterium closely related to.

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Yaws is a tropical infection of the skin, bones and joints caused by the spirochete bacterium . "New treatment schemes for yaws: the path toward eradication" (pdf ). Clinical Infectious Diseases. 55 (3): – doi/cid/cis Yaws has 3 clinical stages: primary, secondary, and tertiary. Stages are interspersed with asymptomatic latent periods. The typical yaws patient is young and. Yaws is the most prevalent infectious, nonvenereal treponemal disease and is caused by Treponema pallidum pertenue. Yaws, endemic.

Signs and symptoms[ edit ] Secondary breakout in a Javanese child age of 12 years. Wax model Within 90 days but usually less than a month of infection a painless but distinctive "mother yaw" nodule appears, which enlarges and becomes warty in appearance. Nearby "daughter yaws" may also appear simultaneously. This primary stage resolves completely within six months. The secondary stage occurs months to years later, with typically widespread skin lesions that vary in appearance, including "crab yaws" on the palms of the hands and soles of the feet with desquamation. These secondary lesions frequently ulcerate and are then highly infectious, but heal after six months or more.

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Yaws - Wikipedia

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A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells. In there were 3, yaws cases in India; in after a serious elimination effort began the number of cases fell to By the number of cases was The last clinical case in India was reported in and the last latent case in The meeting was significant, and representatives of most countries where yaws is endemic attended and described the epidemiological situation at the national level.

As reported at the meeting, in several such countries, mapping of the disease is still patchy and will need to be completed before any serious eradication effort could be enforced. A single oral dose of azithromycin was shown to be as effective as intramuscular penicillin. Epidemiology[ edit ] About three quarters of people affected are children under 15 years of age, with the greatest incidence in children 6—10 years old.

Because T. Mass treatment campaigns in the s reduced the worldwide prevalence from 50— million to fewer than 2.

It is unclear how many people worldwide are infected at present. Following the cessation of this program yaws surveillance and treatment became a part of primary health systems of the affected countries.

However incomplete eradication led to a resurgence of yaws in the s with the largest number of case found in the Western Africa region. Colour diagrams showing a "typical case of Framboesia or Yaws".

Date: Examination of remains of Homo erectus from Kenya , that are about 1. The genetic analysis of the yaws' causative bacteria—Treponema pallidum pertenue—has led to the conclusion that yaws is the most ancient of the four known Treponema diseases.

All other Treponema pallidum subspecies probably evolved from Treponema pallidum pertenue.

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